Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs
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چکیده
منابع مشابه
Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs
Building on our earlier work of attaching a chemosensitizer (reversal agent) to a known drug pharmacophore, we have now expanded the structure-activity relationship study to include simplified versions of the chemosensitizer. The change from two aromatic rings in this head group to a single ring does not appear to detrimentally affect the antimalarial activity of the compounds. Data from in vit...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2017
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01913-16